ADVIA® 1650 Chemistry System

Power - Reliability - Expertise

Microvolume technologyThe ADVIA® 1650 has minimal requirements for sample volume (as low as 2 µL/test), reagent consumption (as low as 80 µL/test) and water consumption (25 L/hour) - thus maximizing management efficiency. Outstanding productivityA rapid, 3-second cycle and system throughput of up to 1650 tests/hour provide powerful high-speed performance, ensure workflow efficiency through peak workloads. Optional universal rack handler facilitates continuous sample feeding for further productivity gains. Unparalleled walkaway capabilityOn-board capacity of 200 samples and 32,000 tests - plus our exclusive Sample Saver Technology for automatic repeat, dilution and reflex testing without operator intervention - optimizes walkaway time, frees you to work on additional tasks. Expertise in automationFor 50 years we have been recognized for our innovation - just as clinical chemistry has been recognized as the driver of automation. The tradition continues. The ADVIA 1650 can be integrated with other testing disciplines via the ADVIA WorkCell™ or ADVIA LabCell® automated sample transportation systems. Technical specifications

Overview Type of System Random, continuous access, batch, discrete processing Throughput Rate 1650 tests/hour, 1200 tests/hour colorimetric, 450 tests/hour ISE Methods Capacity Onboard 49 including 3 ISE

Sample Handling Sample Tubes 2mL, 5 mL, 7 mL, 10 mL sample cups, microcontainer tubes Sample Tray 84 samples, positive sample identification Sample Rack Handler (optional) Universal 5-position rack, 425 total Onboard sample capacity; continous feed Sample Integrity Check Qualitative check for Hemolysis, Lipemia and Icterus STAT Positions 84, not dedicated Bar Codes 2 of 5, code 39, code 128, Codabar (NW7) Auto-repeat Automatic repeat testing from the retained pre-diluted sample or original sample Auto-dilution Automatic dilution from retained pre-diluted sample Auto-reflex Testing Automatic ability to perform 3 additional tests based on results of first test Primary Probe Liquid Level Sensing, Crash Protection, Clot/Clog Detection and Short Sample Detection Secondary Probe Liquid Level Sensing

Microvolume Technology Automatic Sample Pre-dilution Samples diluted 1:5 (30 µL sample + 120 µL saline generates up to 15 test results) pre-dilution tray 120 dilution cups Original Sample Volume 2 to 30 µL; average of 2-3 µL per test Average Reagent Volume 80-120 µL per test Storage Capacity Onboard 20,000 tests average; 32,200 tests maximum

Reaction Area Reaction Tray 221 reusable plastic cuvettes Cuvette Optical Path Length 10 mm Reaction Bath Inert fluorocarbon oil circulation system, 37°C Photometer 14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845 and 884) Light Source 12V, 50W halogen lamp, cooled by forced water circulation Assay Methods Endpoint, rate reaction, 2-point rate, multi-point homogeneous immunoassay Reaction Times 3, 4, 5, 10, 15 and 20 minutes Automatic Correction Serum blank, cell blank, measurement point change, sample volume change in reassay Point Forwarding Automatically extends linearity over assay-range samples

Reagent Handling Reagent Tray 2 trays, 50 positions each, refrigerated Reagent Capacity Onboard 46 colorimetric methods Dispensing System 2 probes with Liquid Level Sensing Reagent Wedges 20, 40, 70 mL barcode labeled wedges Onboard Stability Up to 60 days Reagent Inventory Management Tracks tests remaining, lot number, Onboard stability and expiration date Reagent Dilutions Capability to dilute concentrated reagents Onboard

Open System Capibility Channels 100 channels; includes user-defined applications Bayer 3rd Party Applications Varies by country, can be configured on system

ISE ISE Indirect simultaneous measurement of Na+, K+, Cl- Sample Volume 28 µL for all three tests Priming Automatic priming cycle Electrode Shelf Life 30,000 Samples Throughput Rate 450 tests/hour; 150 tubes/hour

Calibration/QC Calibration Interval Up to 60 days Auto-Calibration/QC User-defined time interval or with new reagent container View Calibration/QC Data Graphical display of calibration curve and QC; real-time QC Calibration/Control Tray 61 refrigerated positions for calibrators, controls and diluents

Data Management Computer Windows NT®, flat panel display SystemDocumentation Operator manual and method sheets on-line Host Interface RS 232C bidirectional Data Storage 70,000 patient samples OnboardMaintenance Logs Schedule and monitor routine maintenance activities via software Host Query ASCII; system requests work-order or batch of work-orders from host

General Specifications Power Requirements 100/110/115/200/220/230 V +/–10%, 26 A, 50/60 Hz, 3 KVA Water Requirements Deionized water from a non-pressurized water reservoir. Maximum consumption: 6.8 gallons per hour (25 liters per hour) Drain Requirements Minimum of 6.8 gallons per hour (25 liters per hour) Dimensions ADVIA 1650:44.45 (h) x 58.27 (w) x 34.13 (d) in., 112.9 (h) x 148.0 (w) x 86.7 (d) cm.ADVIA Rack Handler: 37 (h) x 29 (w) x 41 (d) in.,86.4 (h) x 73.7 (w) x 104.1 (d) cm. Weight ADVIA 1650: 1,178 lbs. (534.3 kg)Universal Rack Handler 178 lbs. (80.7 kg) Compliance UL, cUL, CE Noise Specifications Average with top cover closed 55.91 db Average Heat Output 4,643 Btu/hr. Operating Temperature Range 18°C - 30°C/64°F - 86°F Ambient Humidity 40% - 70%